In our era, the most danger for people with diabetes comes not from ketoacidosis as in the past before discovery of insulin, but from the numerous diabetic complications. One of these diabetic complications is diabetic autonomic neuropathy.
Neuropathies are characterized by a progressive loss of nerve fibers and nerve fiber density, resulting in altered nerve conduction velocity. Neuropathy is on of the most common complications of diabetes, with a lifetime prevalence between 25 and 50 percent in people with diabetes of different kind. » Read more
Following the awarding of the Nobel Prize in medicine (1923) for the discoverers of insulin, Dr, Elliott Joslin predicted that the era of the coma as the central problem of diabetes would give way to the era of diabetes complications. No longer are patients with diabetes dying of diabetic ketoacidosis, insulin has allowed people with diabetes to live longer. Many of this individuals who are not aggressively managed, especially from the onset of diabetes, will develop diabetes complications that are costly to themselves as well as to society. The era of death from diabetic coma was transformed into an era of death from diabetes complications by the discovery of insulin.
» Read more