Meglitinides for Type 2 Diabetes Treatment. Oral Diabetic Medications
Meglitinides drug class for Type 2 diabetes treatment include repaglinide (Prandin) and nateglinide (Starlix) as oral diabetic medications. High fasting insulin levels and a reduction in insulin action may be present in person with Type 2 diabetes symptoms but so is absent or blunted first-phase insulin response to a meal. Most sulfonylureas (except Amaryl glimepiride) increase pancreatic beta-cell insulin secretion as well as plasma insulin concentration in people with Type 2 diabetes symptoms. But sulfonylureas oral diabetic medications fail to improve first-phase insulin release. Here comes meglitinides for Type 2 diabetes treatment. Starlix (nateglinide) and Prandin (repaglinide) as oral diabetic medications do increase first-phase insulin response, allowing to control sugar levels in blood after a meal. Both Starlix 60 mg pills and Prandin 1 mg pills are rapid-acting insulin secretagogues. When Prandin or Starlix meglitinides are taken 15 to 20 minutes before a meal, postprandial glucose excersions can be contained and minimized by this oral diabetic medications. This is important because high glucose level after a meal has been linked to cardiovascular diabetic complication.
Facts about Type 2 diabetes are that hypoglycemia or low blood sugar levels are less common when meglitinides (Starlix nateglinide or Prandin repaglinide) oral diabetes medications are present in Type 2 diabetes treatment plan, not like with sulfonylureas oral diabetes medications. Stimulation of insulin release by Starlix (nateglinide) or Prandin (repaglinide) is rapid, easily reversible, and glucose dependent from beta cells in the pancreas. By reducing postprandial signs of high blood sugar, Prandin repaglinide meglitinide and Starlix nateglinide meglitinide in type 2 diabetes treatment may prove beneficial in slowing down the progression from impaired glucose tolerance symptoms to type 2 diabets symptoms. In low doses, meglitinides oral diabetic medications could be an answer on how to prevent diabetes and diabetes type 2 symptoms in women and men. Attention, in people with prediabetes and impaired glucose tolerance only lowest doses of Prandin meglitinides or Starlix meglitinides should be used in order to avoid low blood sugar symptoms.High doses of nateglinide or repaglinide may bring low blood sugar symptoms that called hypoglycemia.
Meglitinides for Type 2 diabetes treatment are more expensive choice than sulfonylureas oral diabetic medications. Nateglinide (Starlix 120 mg pills) and repaglinide (Prandin 0.5 mg pills and Prandin 2 mg pills buy online now with prescription) are FDA approved for use as monotherapy in Type 2 diabetes treatment and in combination therapy with thiazolidinediones (TZDs) and metformin oral diabetic medications. The effects of Starlix and Prandin meglitinides drugs on improving diabetes complications are likely to be at least similar to those observed with sulfonylureas.
Side effects of meglitinides Prandin (repaglinide) or Starlix (nateglinide) are similar to those of sulfonylureas and include weight gain in patients on Type 2 diabetes treatment.
When used in combination with metformin, meglitinides for Type 2 diabets treatment reduce glycated hemoglobin A1C levels better than either drug used as monotherapy.