Exenatide Drug Loaded Implantable Pump for Type 2 Diabetes

Intarcia Therapeutics Inc. had developed a matchstick-sized device that is aimed to help people with Type 2 sgar diabetes disease. Essentialy it is very small implantable pump loaded with exenatide diabetes drug. Exenatide is marketed in other forms under the brand names Bayetta and Bydureon for treatment of patients with Type 2 sugar diabetes.

Every diabetes management plan has a major big problem in it. Patients constantly fail to stick to the plan. They skip insulin injections or forget to take pills. Health providers can’t monitor day-to-day how Type 2 diabets patients follow prescribed treatment. Most patients will fail at least once a month in their diabetes medication regimen that control their blood sugar.

Exenatide-loaded pump from Intarcia Therapeutics Inc. can be implanted in abdominal tissue of the Type 2 diabetes patient in a matter of minutes by doctor, or even nurse. Once implanted, exenatide-loaded pump delivers a continuous dose of exenatide to Type 2 diabetes patient for up to a one year. This matchstick-sized pump releases exenatide continuously in micro quantities which allow stable constant control of blood sugar.

Two late-stage studies were conducted involving a total of 520 patients with Type 2 diabetes. Studies proved that when used with standard oral diabetes medications, exenatide-loaded implantable pump for Type 2 diabetes significantly lowered blood sugar as measured by a marker called A1C (glycated hemoglobin), when compared in most cases with standard oral diabetes medications alone. These studies pave a good way and bright future for exenatide loaded implantable pump in Type 2 diabetes treatment. Even if patient forget to take oral diabetes medications, Type 2 diabetes still shall be under control thanks to implanted exenatide loaded pump.

Intarcia Therapeutics Inc. pump is called ITCA 650. It is based on modern technology that enables exenatide medicine to remain stable at body temperature.

For people with Type 2 diabetes this technology can be a real life-saver. But still we are looking forward to have artificial pancreas that will closely emulate real thing. I truly believe that our scientists can achieve such a goal in a very near future. Hail to science! 🙂

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