Exenatide (Byetta) for Type 2 Diabetes Treatment

Exenatide drug under brand Byetta is a novel GPL-1 (Glucagon-like Peptide-1) incretin mimetic hormone that has been FDA approved for use in poorly managed Type 2 diabetes individuals using sulfonylureas and metformin pills. Glucagon-like Peptide-1 is secreted from enteroendocrine cells located in the ileum and colon in response to a meal. People with Type 2 sugar diabetes and impaired glucose tolerance are GPL-1 (glucagon-like Peptide-1) deficient. When given before a meal, exenatide (Byetta) restores first-phase insulin response in people with Type 2 diabetes. Exenatide reduces postprandial glucagon levels and increases insulin release from the beta cells. Exenatide (Byetta) injections improve gastric emptying and promotes satiety. It is noted that Byetta (exenatide) appears to reduce beta-cell death (apoptosis). Exenatide (Byetta) functions in a glucose-dependent fashion which means that the effects of the exenatide drug are obvious mainly in the presence of hyperglycemia. You can buy exenatide drug Byetta online now from various vendors following selected links to the right.

Exenatide is a synthetic form of exendin-4 which is GLP-1 autogonist. Exenatide (Byetta) promotes nutrient-stimulated insulin production and release from the pancreas in a glucose-dependent fashion. This means that exenatide will enhance insulin secretion, thereby reducing blood glucose levels as long as the person with Type 2 diabetes is not becoming hypoglycemic! Beta-cell insulin release will diminish as blood glucose levels decrease and glucagon levels will naturally increase to protect the person with Type 2 diabetes against hypoglycemia.

The FDA approved exenatide (Byetta) as adjunctive therapy to improve blood glucose control in people with Type 2 diabetes who are taking metformin, thiazolidiniones (Avandia prescription pills or Actos prescription pills that you can buy online now), a sulfonylurea, a combination of metformin plus sulfonylurea, or a combination of metformin and a thiazolidiniones. Studies show that people with Type 2 diabetes using exenatide (Byetta) injections experiencing weight loss. In an open label extension trial, 393 individuals with type 2 diabetes taking exenatide injections for 82 weeks lost on average of 8 to 10 pounds of body weight.

Exenatide (Byetta) is usually prescribed as supportive therapy to improve glycemic control in people on type 2 diabetes treatment. The initial dose of exenatide is given twice daily using a pen injector within one hour of a meal. Byetta exenatide may be injected in the arm, the abdomen, or the leg. There is no need to adjust the dose of exenatide based on food consumption or activity levels, unlike insulin dose, because of the glucose-dependent insulin action of the exenatide (Byetta) drug. Using exenatide therapy for type 2 diabetes treatment you can lower A1C levels and experience beneficial weight loss.

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