Depression and Diabetes. Diabetic Complications

Men and women in whom both diabetes mellitus and depression are likely to develop are usually struggling with obesity, smoke cigarettes, and have inactive ‘couch potato’ lifestyle. These people are in risk group for coronary artery disease because of elevatec C-reactive protein levels.
Although depression often precedes the onset of type 2 diabetes by 6 to 8 years, people with mental illness are at high risk for developing diabetes disease and ling-term diabetic complications including macrovascular disease and microvascular disease.Many newly diagnosed individuals with type 2 diabetes symptoms relate the onset of their depression with the time when they got signs and symptoms of diabetes. Facts about diabetes prove this wrong. Around 80 percent of people with type 2 diabetes symptoms have had a major depression event before their diagnosis with type 2 diabetes.

Major depression disorder (MDD) has been found to be a chronic or recurrent illness in most people with type 2 diabetes symptoms. More facts about diabets and depression: obesity, clinically severe obesity, high blood glucose levels, higher glycated hemoglobin A1C levels, sedentary lifestyle, and tobacco smoking are much more common in people with symptoms of type 2 diabetes who are also depressed. Diabetes symptoms in men and diabetes symptoms in women are much more pronounced with depression and major depression disorder.

Depression in patients with Type 2 diabetes promotes sedentary lifestyle and obesity as a result of such a lifestyle. Diabetes symptoms in women plus depression plus nicotine abuse from chain smoking leads to severe diabetic complications. It is very hard to persuade obese person with Type 2 diabetes symptoms to enter weight-loss program and adopt diabetic diet or insulin resistance diet if depression or major depression disorder are out of control.

Individuals with Type 2 diabetes who have major depression disorder have difficulty in achieving normal blood sugar range and to keep on glycated hemoglobin A1C level of less than 8 percent. Elevated A1C levels are associated with depression in younger patients on Type 2 diabetes treatment plan. Major depression disorder (MDD) has been shown to be associated with much higher risk of death for patients with diabetes type 2 symptoms.

Diabetes symptoms in men are much less associated with major depression disorder than diabetes symptoms in women. But major diabetic complications are more often diagnosed in men with coexisting depression and diabetes. Treatment costs over a 3-year period for depressed person with diabetes symptoms average $32,000 versus $22,000 for those people on Type 2 diabetes treatment without depression.

People with depression and diabetes tend to increase use of cigarettes which leads to elevated insulin resistance, high blood pressure, proinflammatory state, and reduced nitric oxide synthetase. Patients on Type 2 diabetes treatment experiencing depression or major depression disorder may lumber towards physical inactivity that lead to increased  fatigue, obesity and clinically severe obesity, increase in diabetic peripheral neuropathic pain symptoms, and sleep disturbance. Obesity and increasing weight in men and women with type 2 diabetes symptoms and depression will result in hypertension, hyperlipidemia, inflammatory cytokines, prothrombotic state, reduced adiponectin, and increase in counterregulatory hormones such as glucagon, cortisol, and catechoalamines.

Depression symptoms must be treated with tricyclic antidepressants such as Amitriptyline and Desipramine.

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